THE INTEGRIN ANTAGONIST CILENGITIDE ACTIVATES ALPHAVBETA3, DISRUPTS VE-CADHERIN LOCALIZATION AT CELL JUNCTIONS AND ENHANCES PERMEABILITY IN ENDOTHELIAL CELLS.

Cilengitide is a high-affinity cyclic pentapeptdic alphaV integrin antagonist previously Tampers reported to suppress angiogenesis by inducing anoikis of endothelial cells adhering through alphaVbeta3/alphaVbeta5 integrins.Angiogenic endothelial cells express multiple integrins, in particular those of the beta1 family, and little is known on the ef

A kind of composite modified asphalt Tampers with high elasticity was prepared by SBS and high elasticity agent, and the asphalt mixture with easy compactness was applied.The high temperature, low temperature, water stability and fatigue properties of the mixture were evaluated by laboratory tests.The results show that the optimum content of high e

Kevin Nugent,1 Wallace Smart2,3 1Kinark Child and Audio Video Connector Family Services, Trent University and Sir Sanford Fleming College, Peterborough, ON, Canada; 2Department of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; 3University of Lethbridge Health Centre, Lethbridge, AB, Canada Abstract: A Pu

It has been reported that a suit of plant traits can regulate the ant-seed interaction and subsequently affect the seed dispersal.However, the role of plant volatiles in attracting the ants for seed dispersal remains little examined.We used a Y-tube olfactometer to test behavior response of a keystone seed-dispersing ant (Pristomyrmex pungens Mayr)

Quartz crystal resonators coated with gas-sorptive films were characterized by analyzing their structures and their organic gas-sorption behaviors, which were then studied using statistics and computational molecular simulations.The films had carbonaceous structures that were prepared by radio-frequency (rf) sputtering of aromatic biomolecules, suc